Dr. Tan Yu Qian

Position:Patent Scientist
Email:yuqian.tan@spruson.com
Tan Yu Qian

Academic Qualifications

Qualification Institution Year of Completion
Graduate Diploma in Intellectual Property and Innovation Management (GDIPIM) with specialization in Patent Agency Singapore University of Social Sciences2021
Doctor of Philosophy (Chemistry)Nanyang Technological University, Singapore2017
Bachelor of Science (Chemistry) (Hons) National University of Singapore2011

Industry Experience

PositionOrganisation/InstitutionDate of Tenure
Postdoctoral ResearcherNational Institute of Education2016 - 2018

Selected Publications – industry/IP Specific

Publications
“Acetal-Functionalized RAPTA Complexes for Conjugation and Labeling". Organometallics. 30 (21): 5965–71
Experience and Technical Background

Experienced in the following areas of patent practice:

  • Patent prior art search
  • Local and foreign patent prosecution
  • Patent drafting

Primary patent practice areas by technology:

  • Bioinorganic chemistry
  • Conjugation methods
  • Pharmaceutical compositions
  • Bioorganometallic chemistry
  • Synthetic chemistry

Research/industry background:

A. General technical areas:

  • Synthetic organic/ inorganic chemistry
  • Conjugation methods
  • Bioorganometallic chemistry
  • Nucleotide chemistry

B. Honours research:

  • Functionalization of Ruthenium (II) arene PTA complexes for mechanistic studies
  • In-situ labelling of functionalized ruthenium (II) arene PTA complexes with fluorophores

C. PhD research:

  • Synthesis and characterization of functionalized osmium carbonyl cluster complexes
  • Conjugation of osmium cluster complexes to biomolecules such as nucleotides and peptides
  • Application of osmium cluster – biomolecule conjugates as labels for electron microscopy of DNA molecules
  • Use of osmium cluster conjugates as pH indicators, detectable using Raman spectroscopy
  • In vitro evaluation of osmium cluster conjugates for potential anti-proliferative activity on hormone dependent and hormone independent breast cancer cells

D. Industry experience:

  • Synthesis and characterization of copper (II) semicarbazone complexes which are able to bind to G-quadruplexes.
  • Study of the physicochemical properties of copper (II) complexes which influence its biological activity

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