Dr. Nicole Khong

Position:Patent Scientist

Academic Qualifications

Qualification Institution Year of Completion
Doctor of Philosophy (Biological Sciences)Nanyang Technological University2017
Bachelor of Science (Biological Sciences) (Hons)Nanyang Technological University2012

Industry Experience

PositionOrganisation/InstitutionDate of Tenure
Postdoctoral Research FellowNanyang Technological UniversityMay 2017 – June 2021

Selected Publications – industry/IP specific

Khong, N. Z., Zeng, Y., Lai, S. K., Koh, C. G., Liang, Z. X., Chiam, K. H., & Li, H. Y. (2021). Dynamic swimming pattern of Pseudomonas aeruginosa near a vertical wall during initial attachment stages of biofilm formation. Scientific reports, 11(1), 1952.
Khong, Z. J., Lai, S. K., Koh, C. G., Geifman-Shochat, S., & Li, H. Y. (2020). A novel function of AAA-ATPase p97/VCP in the regulation of cell motility. Oncotarget, 11(1), 74–85.
Sheng S, Xin L, Yam JKH, Salido MM, Khong NZJ, Liu Q, Chea RA, Li HY, Yang L, Liang Z-X and Xu L (2019) The MapZ-Mediated Methylation of Chemoreceptors Contributes to Pathogenicity of Pseudomonas aeruginosa. Front. Microbiol. 10:67.
Experience and Technical Background

Primary patent practice areas by technology:

  • Proteomics
  • Microbiology
  • Oncology

Research/industry background:

A. General technical areas:

  • Advanced Microscopy
  • Proteomics
  • Microbiology
  • Oncology
  • Drug discovery

B. Honours research:

  • Investigated the role of Kinesin family member 4A (KIF4A) in the proliferation of cancer cells

C. PhD research:

  • Identified a novel function of AAA-ATPase p97/VCP in the regulation of cell motility

D. Industry experience:

  • Extraction, isolation and characterization of bioactive compounds in locally grown Asian folk medicinal herbs and anti-cancer research of selected active compounds.
  • Investigated Host-Pathogen interactions between infectious bacteria Pseudomonas aeruginosa and mammalian macrophages: How mutant P. aeruginosa evade macrophage phagocytosis.
  • DNA content and invasiveness: The correlation between Plasmodium Falciparum nuclear DNA content and parasite invasive capacity.
  • Bio-imaging applications of Halide perovskite nanocrystals.

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