IP Qualifications
| Qualification |
|---|
| Registered Australian and New Zealand Patent Attorney |
| Registered Australian Trade Mark Attorney |
Academic Qualifications
| Qualification | Institution | Year of Completion |
|---|---|---|
| Doctor of Philosophy (PhD) | University of New England | 2004 |
| Bachelor of Science (Hons) | University of Adelaide | 1999 |
Postdoctoral Research Experience
| Position | Organisation/Institution | Date of Tenure |
|---|---|---|
| Postdoctoral Research Fellow | University of Queensland | 2004-2005 |
| Senior Postdoctoral Research Fellow | University of Queensland | 2009-2011 |
Industry Experience
| Position | Organisation/Institution | Date of Tenure |
|---|---|---|
| Lead Researcher (Head of Nanomaterials Division) | Botswana Institute for Technology Research and Innovation | 2014-2016 |
| Principal Research Scientist (Head of Food Chemistry Department) | Botswana National Food Technology Research Centre | 2011-2014 |
| Medicinal Chemist/Project Manager | Progen Pharmaceuticals | 2005-2009 |
Fellowships/Memberships/Affiliations
| Organisation | Level |
|---|---|
| The Institute of Patent and Trade Mark Attorneys of Australia | Member |
Selected Patent Cooperation (PCT) Specification
| PCT Publication Number | Title of Application |
|---|---|
| WO2018/102848 | Extruded Polyacrylonitrile Copolymer |
Selected Publications - Patent
| Scientific Publications |
|---|
| Ferro, Karoli, Lui, Handley, Johnstone et al. “Novel sulfated oligosaccharide derivatives”; AU 2008314505 B2, CA 2704201 C, EP 2205616 B1, JP 5509084 B, US 8,828,952, CN 101874035 B, IN 274501, IL 205143, RU2483074C2, KR101646960B1 |
Selected Publications - Scientific
| Scientific Publications |
|---|
| Pandey, Johnstone et al. (2014) “Solution-processed pentathiophene dendrimer based photodetectors for digital cameras”, Sensors and Actuators B: Chemical, 196, 245-251. |
| Ferro, Liu, Johnstone et al. (2012) “Discovery of PG545: A highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis”, J. Med. Chem., 55(8): 3804-3813. |
| Van Vuuren, Johnstone et al. (2010) “Determining the absorption tolerance of single chromophore photodiodes for machine vision”, App. Phys. Lett., 96, 253303-253305, 2010 |
| Said, Trybala, Andersson, Johnstone et al. (2010) “Lipophile-conjugated sulfated oligosaccharides as novel microbicides against HIV-1”, Antiviral Research, 86(3), 286-295. |
| Ekblad, Adamiak, Bergström, Johnstone et al. (2010) “A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virus”, Antiviral Research, 86(2), 196-203. |
| Johnstone et al. (2010) “Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth”, J. Med. Chem., 53(4), 1686–1699. |
| Dredge, Hammond, Davis, Li, Lui, Johnstone et al. (2010) “The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy”, Invest. New Drugs., 28(3), 276-283. |
| Lui, Johnstone et al. (2009) “An improved synthetic route to the potent angiogenesis inhibitor benzyl Manα(1→3)-Manα(1→3)-Manα (1→3)-Manα(1→2)-Man Hexadecasulfate”, Aust. J. Chem., 62(6) 546-552. |
| Mullen, Johnstone et al. (2009) “Crown-ether- and porphyrin-attached gel-phase resins in thermodynamically controlled rotaxane assembly”, Org. Biomol. Chem., 7(2) 293-303. |
| Merican, Johnstone et al. (2008) “Porphyrin-naphthodiimide interactions as a structural motif in foldamers and supramolecular assemblies”, Org. Biomol. Chem., 6(14) 2534-2543. |
| Mullen, Johnstone et al. (2008) “Monitoring the thermodynamically-controlled formation of diimide-based resin-attached rotaxanes by gel-phase HR MAS 1H NMR spectroscopy”, Org. Biomol. Chem., 6(2) 278-286. |
| Fairweather, Johnstone et al. (2008) “Synthesis and heparanase inhibitory activity of sulfated mannooligosaccharides related to the antiangiogenic agent PI-88”, Bioorg. Med. Chem., 16(2) 699-709. |
| Johnstone et al. (2006) “Gel-phase HR-MAS 1H NMR spectroscopy as a probe for solid-tethered diimide rotaxanes and catenanes”, New J. Chem., 30: 861-867. |
Experience and Technical Background
Experienced in the following areas of patent practice:
- Patent Drafting
- Local and Foreign Patent Prosecution
- Extensions of Patent Term (Pharmaceuticals)
- Patentability Advice
- Freedom to Operate Opinions
- Oppositions
Primary patent practice areas by technology:
- Organic Chemistry
- Pharmaceuticals
- Materials Chemistry
Research background:
General technical areas:
- Organic Chemistry
- Synthetic Chemistry
- Pharmaceuticals
- Materials Chemistry
- Food Chemistry
- Diagnostics
Honours research:
- Porphyrin and pyrrole synthetic chemistry
PhD research:
- Supramolecular synthetic chemistry (rotaxanes and catenanes).
- Solution and solid-state host-guest chemistry.
Postdoctoral research:
-
- Enzymatic synthesis of oligosaccharide-linked peptides for enhanced drug delivery.
- Oral delivery of modified luteinizing hormone-releasing hormone derivatives.
- Digital camera organic photodiodes.
Industry experience:
- Medicinal chemistry: multiple growth factor binders and heparanase inhibitors.
- Inventor on family of granted patents.
- Drug discovery and development to phase 1 clinical.
- Analysis of biochemistry, cell biology, preclinical toxicology and preclinical efficacy results.
- Scale-up process development chemistry.
- Optimisation of manufacturing process and analysis of process by-products for phase 3 clinical candidate.
- Water purification research and product development.
- Foot and mouth disease field diagnostic kit development.
- Coal to chemicals research.
- Mycotoxins food safety analysis, assay development and risk assessment.
- Pesticides food safety analysis and risk management.
- Traditional food composition analysis.
- Sorghum vitamin A fortification product development.