Dr. Elizabeth Barrett

Position:Principal
Email:elizabeth.barrett@spruson.com
Elizabeth Barrett

IP Qualifications

Qualification
Registered Australian and New Zealand Patent Attorney
Registered Australian Trade Mark Attorney

Academic Qualifications

QualificationInstitutionYear of Completion
Master of Industrial PropertyUniversity of Technology, Sydney2009
Doctor of Philosophy (PhD)Australian National University2004
Bachelor of Advanced Science (Hons I & University Medal)University of Sydney2000

Postdoctoral Research Experience

PositionOrganisation/InstitutionDate of Tenure
Postdoctoral FellowThe Scripps Research Institute (La Jolla, California)2004 – 2007

Fellowships/Memberships/Affiliations

OrganisationLevel
The Institute of Patent and Trade Mark Attorneys of AustraliaMember
The Intellectual Property Society of Australia and New ZealandMember

Selected Patent Cooperation Treaty (PCT) Specifications

PCT Publication NumberTitle of Application
WO2018/107205Radiolabelled material for targeted administration
WO2018/000010Haloallylamine Pyrazole derivative inhibitors of Lysyl oxidases and uses thereof
WO2017/136870Haloallylamine Indole and Azaindole derivative inhibitors of Lysyl oxidases and uses thereof
WO 2012/071611Histone inhibition
WO 2011/109877Heparansulfate replacement therapy
WO 2011/003129Treatment of non-neuronal and non-myocardial cell, tissue and organ damage and associated pain with persistent sodium current blockers
WO 2010/096869An agent for improving inotropy and lusitropy, and for treating diseases causing or caused by poor contractility or relaxation of the heart
WO 2009/043114Arsenoxide compound and method of use
WO 2009/026658PPar agonists

Selected Publications - Scientific

Scientific Publication
Barrett et al. (2008), “Stability, Dynamics and Selectivity in the Assembly of Hydrogen Bonded Hexameric Capsules”, J. Am. Chem. Soc. 130:2344
Barrett et al. (2007), “Self-assembly dynamics of a cylindrical capsule monitored by fluorescence resonance energy transfer”, J. Am. ChemSoc 129(28):8818-24
Barrett et al. (2007), “Assembly and exchange of resorcinarene capsules monitored by fluorescence resonance energy transfer”, J. Am. ChemSoc 129:3818–3819.
Barrett et al. (2007), “Synthesis and assembly of monofunctionalized pyrogallolarene capsules monitored by fluorescence resonance energy transfer”, Chem.Commun. (41):4224-6
Barrett et al. (2005), “Practical synthesis and guest-guest communication in multi-hemicarceplexes”, Chem.Commun. (2005), (27), 3418-3420.
Barrett et al. (2004), “Superbowl container molecules”, Journal of the American Chemical Society, vol. 126, no. 51, pp. 16747-16749
Barrett et al. (2002), “Partial etherification reactions of cavitand phenol bowls”, Aust. J. Chem. (2002), 55, 319-325
Experience and Technical Background

Experienced in the following areas of patent practice:

  • Patent Drafting
  • Local & Foreign Patent Prosecution
  • Patent Litigation
  • Patent Oppositions
  • Patentability Advice
  • Extensions of Patent Term (Pharmaceuticals)

Primary parent practice areas by technology:

  • Organic Chemistry
  • Pharmaceuticals

Research background:

A. General technical areas:

  • Organic Chemistry
  • Supramolecular Chemistry
  • Synthetic Organic Chemistry
  • Cavitands

B. Honours research:

  • Research in the area of synthetic organic chemistry,
    in particular synthetic supramolecular chemistry.
  • Development of selective functionalisation protocols
    to access unsymmetrically substituted cavitands which are
    important building blocks in host/guest chemistry.
  • These functionalised cavitands were utilised to prepare
    multicavit and arrays to explore the controlled capture and
    release of guest molecules.

C. PhD research:

  • Selective functionalisation protocols for cavitands were
    utilised to prepare novel supramolecular architectures and the
    application of these supramolecular arrays was explored in the
    area of host/guest chemistry.
  • Chiral cavitands were synthesised and utilised in the preparation
    of chiral hemicarcerands.
  • Selective guest binding of small racemic guest molecules was
    investigated with these chiral hemicarcerands.
  • The first covalently linked “superbowl” container molecule
    constructed from five cavitand bowls and investigations made
    into complexation properties of this large host with an interior
    of ca. 1050 Å3.
  • NMR spectroscopy was utilised to study host/guest interactions,
    including selectivity of binding within chiral cavitands.
  • Collaborative study undertaken on the use of boronic acid
    functionalised cavitands in the selective transport of sugars across
    lipophilic membranes, with potential application in drug delivery.

D. Postdoctoral research:

  • Synthetic organic chemistry leading to the synthesis of
    functionalised capsules.
  • The design and synthesis of fluorescently labelled esorcinarenes
    was developed and labelled compounds were utilised in
    fluorescence resonance energy transfer (FRET) and NMR
    spectroscopy studies to investigate the dynamic self-assembly of
    hydrogen bonded capsules.

Would you like to join the Spruson & Ferguson team?


Work For Us

Contact our Expert Team

Contact Us