|Registered Australian and New Zealand Patent Attorney|
|Registered Australian Trade Mark Attorney|
|Qualification||Institution||Year of Completion|
|Master of Industrial Property||University of Technology, Sydney||2009|
|Doctor of Philosophy (PhD)||Australian National University||2004|
|Bachelor of Advanced Science (Hons I & University Medal)||University of Sydney||2000|
Postdoctoral Research Experience
|Position||Organisation/Institution||Date of Tenure|
|Postdoctoral Fellow||The Scripps Research Institute (La Jolla, California)||2004 – 2007|
|The Institute of Patent and Trade Mark Attorneys of Australia||Member|
|The Intellectual Property Society of Australia and New Zealand||Member|
Selected Patent Cooperation Treaty (PCT) Specifications
|PCT Publication Number||Title of Application|
|WO2018/107205||Radiolabelled material for targeted administration|
|WO2018/000010||Haloallylamine Pyrazole derivative inhibitors of Lysyl oxidases and uses thereof|
|WO2017/136870||Haloallylamine Indole and Azaindole derivative inhibitors of Lysyl oxidases and uses thereof|
|WO 2012/071611||Histone inhibition|
|WO 2011/109877||Heparansulfate replacement therapy|
|WO 2011/003129||Treatment of non-neuronal and non-myocardial cell, tissue and organ damage and associated pain with persistent sodium current blockers|
|WO 2010/096869||An agent for improving inotropy and lusitropy, and for treating diseases causing or caused by poor contractility or relaxation of the heart|
|WO 2009/043114||Arsenoxide compound and method of use|
|WO 2009/026658||PPar agonists|
Selected Publications - Scientific
|Barrett et al. (2008), “Stability, Dynamics and Selectivity in the Assembly of Hydrogen Bonded Hexameric Capsules”, J. Am. Chem. Soc. 130:2344|
|Barrett et al. (2007), “Self-assembly dynamics of a cylindrical capsule monitored by fluorescence resonance energy transfer”, J. Am. ChemSoc 129(28):8818-24|
|Barrett et al. (2007), “Assembly and exchange of resorcinarene capsules monitored by fluorescence resonance energy transfer”, J. Am. ChemSoc 129:3818–3819.|
|Barrett et al. (2007), “Synthesis and assembly of monofunctionalized pyrogallolarene capsules monitored by fluorescence resonance energy transfer”, Chem.Commun. (41):4224-6|
|Barrett et al. (2005), “Practical synthesis and guest-guest communication in multi-hemicarceplexes”, Chem.Commun. (2005), (27), 3418-3420.|
|Barrett et al. (2004), “Superbowl container molecules”, Journal of the American Chemical Society, vol. 126, no. 51, pp. 16747-16749|
|Barrett et al. (2002), “Partial etherification reactions of cavitand phenol bowls”, Aust. J. Chem. (2002), 55, 319-325|
Experience and Technical Background
Experienced in the following areas of patent practice:
- Patent Drafting
- Local & Foreign Patent Prosecution
- Patent Litigation
- Patent Oppositions
- Patentability Advice
- Extensions of Patent Term (Pharmaceuticals)
Primary parent practice areas by technology:
- Organic Chemistry
A. General technical areas:
- Organic Chemistry
- Supramolecular Chemistry
- Synthetic Organic Chemistry
B. Honours research:
- Research in the area of synthetic organic chemistry,
in particular synthetic supramolecular chemistry.
- Development of selective functionalisation protocols
to access unsymmetrically substituted cavitands which are
important building blocks in host/guest chemistry.
- These functionalised cavitands were utilised to prepare
multicavit and arrays to explore the controlled capture and
release of guest molecules.
C. PhD research:
- Selective functionalisation protocols for cavitands were
utilised to prepare novel supramolecular architectures and the
application of these supramolecular arrays was explored in the
area of host/guest chemistry.
- Chiral cavitands were synthesised and utilised in the preparation
of chiral hemicarcerands.
- Selective guest binding of small racemic guest molecules was
investigated with these chiral hemicarcerands.
- The first covalently linked “superbowl” container molecule
constructed from five cavitand bowls and investigations made
into complexation properties of this large host with an interior
of ca. 1050 Å3.
- NMR spectroscopy was utilised to study host/guest interactions,
including selectivity of binding within chiral cavitands.
- Collaborative study undertaken on the use of boronic acid
functionalised cavitands in the selective transport of sugars across
lipophilic membranes, with potential application in drug delivery.
D. Postdoctoral research:
- Synthetic organic chemistry leading to the synthesis of
- The design and synthesis of fluorescently labelled esorcinarenes
was developed and labelled compounds were utilised in
fluorescence resonance energy transfer (FRET) and NMR
spectroscopy studies to investigate the dynamic self-assembly of
hydrogen bonded capsules.