Academic Qualifications
| Qualification | Institution | Year of Completion |
|---|---|---|
| Graduate Diploma in Intellectual Property and Innovation Management (GDIPIM) with specialization in Patent Agency | Singapore University of Social Sciences | 2019 |
| Bachelor of Science (Life Sciences) (Honours) | National University of Singapore | 2010 |
Industry Experience
| Position | Organisation/Institution | Date of Tenure |
|---|---|---|
| Patent Associate | Horizon IP Pte Ltd | April 2019 – Feb 2022 |
| Research Associate | Hummingbird Bioscience Pte Ltd | Dec 2017 – April 2019 |
| Research Officer | GIS Astar | June 2016 – Dec 2017 |
| Research Associate | Veredus Laboratories Pte Ltd | April 2014 – June 2016 |
| Research Assistant | NUHS/NUS | August 2011 – April 2014 |
Selected Publications – industry/IP specific
| Publications |
|---|
| A comparative study of tumour-on-chip models with patient-derived xenografts for predicting chemotherapy efficacy in colorectal cancer patients; Front. Bioeng. Biotechnol., 16 August 2022 Sec. Biomaterials, Volume 10 – 2022; Louis Jun Ye Ong, Shumei Chia, Stephen Qi Rong Wong, Xiaoqian Zhang, Huiwen Chua, Jia Min Loo, Wei Yong Chua, Clarinda Chua, Emile Tan, Hannes Hentze, Iain Beehuat Tan, Ramanuj DasGupta and Yi-Chin Toh. |
| Paper‐based MicroRNA Expression Profiling from Plasma and Circulating Tumor Cells; Chem . 2017 Mar;63(3):731-741. Leong, Sai Mun; Tan, Karen Mei‐Ling; Chua, Huiwen; Huang, Mo Chao; Cheong, Wai Chye; Li, Mo‐Huang; Tucker, Steven; Koay, Evelyn Siew‐Chuan Clin |
| Highly sensitive KRAS mutation detection from formalin‐fixed paraffin‐embedded biopsies and circulating tumour cells using wild‐type blocking polymerase chain reaction and Sanger sequencing. Mol Diagn Ther., 18(4):459‐68. Huang MM, Leong SM, Chua HW, Tucker S, Cheong WC, Chiu L, Li MH, Koay ES. (2014). |
| Utility of microsieve device for enumeration and miRNA expression profiling of CTCs for personalized cancer management. J Clin Oncol 31, suppl; abstract e22107. (Abstract submitted during 2013 ASCO Annual MeetingSteven Tucker, Karen Mei Ling Tan, Sai Mun Leong, Chua Hui Wen, Delly Fareda Jumaat, Doreen Chek Yee Tan, Mo‐Huang Li, Evelyn S. C. Koay (2013). |
Experience and Technical Background
Experienced in the following areas of patent practice:
- Filing and Prosecution work
Primary patent practice areas by technology:
- Life sciences
Research/industry background:
A. General technical areas:
- Cancer Biology
- Microbiology & Genetic Engineering
- Bioinformatics
- Immunology & Antibodies
B. Honours research:
- Research on Ezrin protein signalling pathway and its function in CNS
C. Industry experience:
- involved in filing and prosecuting US applications
- Involved in Antibody and Protein engineering development using Yeast Display and Mammalian Cells Display Platform, as well as mechanism study of lead antibodies candidate
- Involved in direct generation of 2D cancer cell lines and 3D tumor organoids from clinical colorectal samples to be used for high throughput drug compounds screening; generating high complexity plasmid libraries of barcodes in patient‐derived colorectal cancer cell lines and setting up drug‐resistant models
- developed microarray assay for Ethnic groups classification, involved in the design phase of a microarray assay for the detection of the Influenza Flu viruses subtypes
- involved in studying molecular characteristics of captured circulating tumour cells (CTCs) from patients’ blood samples (mainly Breast and Colorectal cancer