Alex Gan

Position:Patent Scientist
Email:alex.gan@spruson.com

Academic Qualifications

Qualification Institution Year of Completion
Doctor of Philosophy (Chemistry)National University of Singapore 2020
Bachelor of Science (Honours) (Chemistry)National University of Singapore2014

Industry Experience

PositionOrganisation/InstitutionDate of Tenure
Research FellowNational University of SingaporeAugust 2019 – October 2020
Research AssistantNational University of SingaporeAugust 2018 – July 2019

Selected Publications – industry/IP specific

Publications
Wu, C.-H. et al. A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation By Autophagy Induction. Front Immunol. 2020, 11, 3330
Gan, C. H. et al. H-Phosphonate Synthesis And Biological Evaluation Of An Immunomodulatory Phosphoglycolipid From Thermophilic Bacteria. Org. Lett. 2020, 22(7), 2569
Hsieh, C.-Y. et al. Synthetic 4-Hydroxy Auxaconjugatin B, A Novel Autophagy Inducer, Attenuates Gouty Inflammation By Inhibiting The NLRP3 Inflammasome. Cells 2020, 9, 279.
Experience and Technical Background

Primary patent practice areas by technology:

  • Organic Chemistry
  • Pharmaceuticals

 

Research/industry background:

A. General technical areas:

  • Medicinal Chemistry
  • Organic Chemistry

B. Honours research:

  • Medicinal Chemistry
  • Organic Chemistry
  • Synthesis and Biological Evaluation of Chondroitin Sulfate analogues

C. PhD/ Industry research:

  • Medicinal Chemistry
  • Organic Chemistry
  • Synthesis and Biological Evaluation of PGL-1 Analogues
  • Synthesis of Polyenylpyrrole Derivatives with Potential Anti-inflammatory Activities

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