Dr. Natsuho Yamamoto

Natsuho Yamamoto

IP Qualifications

Registered Singapore Patent Attorney

Academic Qualifications

Qualification Institution Year of Completion
Graduate Certificate in Intellectual Property Law (Distinction)National University of Singapore2015
Doctor of Philosophy (Science)University of Sydney, Australia2011
Bachelor of Science (Chemistry) (Advanced) (Hons I)University of Sydney, Australia2006

Industry Experience

PositionOrganisation/InstitutionDate of Tenure
Postdoctoral ResearcherNorthwestern University, USA2011 - 2013

Selected Patent Cooperation Treaty (PCT) Specifications

PCT Publication NumberTitle of Application
PCT/SG2015/050038 Fused pyrimidine-based hydroxamate derivatives
PCT/SG2016/050019 Fillers for polymers
PCT/SG2016/050104Composite material for drug delivery
PCT/SG2017/050085 Durable hydrophobic coating composition
PCT/SG2017/050198A multimodal fluorescent probe
PCT/SG2018/050342Cell-penetrating glycosaminoglycan mimetics
PCT/SG2019/050146Thermal control system
Experience and Technical Background

Experienced in the following areas of patent practice:

  • Local & Foreign Prosecution
  • Patent Drafting
  • Searches/Opinions
  • Litigation support
  • Validity & Infringement
  • Strategic Advice
  • Patentability Advice

Primary patent practice areas by technology:

  • Materials
  • Pharmaceuticals
  • Polymers
  • Organic chemistry
  • Inorganic Chemistry
  • Chemical Engineering

Research/industry background:

A. General technical areas:

  • Bioinorganic Medicinal Chemistry
  • Cell imaging
  • Metal complexes
  • Peptide chemistry

B. Honours research:

  • Investigated the use of cobalt complexes as chaperones for anticancer agents

C. PhD research:

  • Investigated the use of cobalt-complexes that release their ligands only in hypoxic environments, for specific delivery of antitumour agents in hypoxic regions of solid tumours. Synthesized the ligands and complexes and tested the hypothesis in cells as well as in vitro tumor models such as spheroids using fluorescence microscopy.
  • Investigated the use of peptides that enter cells only in the presence of tumour-specific enzymes for specific delivery of antitumour agents in tumours. Synthesized the peptides and tested the hypothesis in in cells as well as in vitro tumour models using fluorescence microscopy.

D. Industry experience:

  • Worked as a postdoctoral fellow at Northwestern University, in a project on cobalt complexes that selectively inhibit proteins such as zinc finger transcription factors, matrix metalloproteinases and metallo-ß-lactamases that contain histidine residues in the active site.

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