Dr. Catherine Winbanks

Position:Senior Associate
Email:catherine.winbanks@spruson.com

IP Qualifications

Qualification
Registered Australian and New Zealand Patent Attorney

Academic Qualifications

QualificationInstitutionYear of Completion
Master of Intellectual Property LawUniversity of Melbourne2016
Doctor of Philosophy (PhD)RMIT University2008
Bachelor of Applied Science (Human Biology)RMIT University2002

Postdoctoral Research Experience

PositionOrganisation/InstitutionDate of Tenure
Senior Research Fellow Baker Heart and Diabetes Institute2009-2014
Post-doctoral Researcher The University of Melbourne2008

Fellowships/Memberships/Affiliations

Organisation Level
The Institute of Patent and Trade Mark Attorneys Australia (IPTA)Ordinary member
AusBiotechCorporate Member
BioMelbouneCorporate Member

Selected Patent Cooperation Treaty (PCT) specifications

PCT Publication NumberTitle of Application
WO 2018/176099Treatment of respiratory infection with a TLR2 agonist
WO 2019/060960Method of prognosis
WO 2019/061396Method of prognosis
WO 2020/243787Anti-inflammatory agents
WO 2019/119069Administration of a TLR2 agonist for the treatment or prevention of a respiratory condition associated with an infectious agent
WO 2019/169448 Multi-specific antibodies
WO 2019/161449Short/small hairpin RNA molecules
WO 2017/219078Allosteric regulation of haemostatic activity
WO 2019/010533Treatment of ocular conditions
WO 2020/077380Methods and compositions for treating tauopathies
WO 2020/172713Acoustic energy treatment

Selected Publications - Scientific

Scientific Publications
Winbanks CE et al., ”Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice”, Sci Transl Med. 2016 Jul 20;8(348):348
Winbanks CE, et al., MicroRNAs differentially regulated in cardiac and skeletal muscle in health and disease: potential drug targets?”, Clin Exp Pharmacol Physiol., 2014 Sep;41(9):727-37
Chen JL, Walton KL, Winbanks CE et al., “Elevated expression of activins promotes muscle wasting and cachexia”, FASEB J., 2014 28(4):1711-23
Wang B, Koh P, Winbanks C, et al., “miR-200a Prevents renal fibrogenesis through repression of TGF-β2 expression”, Diabetes, 2011 60(1):280-7
Winbanks CE et al., “The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass”, J Cell Biol., 2013 203(2):345-57
Winbanks CE, et al., “Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin”, J Cell Biol., 2012 97(7):997-1008
Bernardo BC, Nguyen SS, Winbanks CE et al., “Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy”, FASEB J., 2014 28(12):5097-110
Wang B, Komers R, Carew R, Winbanks CE et al., “Suppression of microRNA-29 expression by TGF-β1 promotes collagen expression and renal fibrosis”, J Am Soc Nephrol., 2012 23(2):252-65
Winbanks CE et al., “TGF-beta regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4” J Biol Chem., 2011 286(16):13805-14
Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, et al., Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo”, PLoS Genet., 2010 Jan 15;6(1)
Winbanks CE et al., “Role of the phosphatidylinositol 3-kinase and mTOR pathways in the regulation of renal fibroblast function and differentiation”, Int J Biochem Cell Biol. 2007;39(1):206-19
Experience and Technical Background

Experienced in the following areas of patent practice:

  • Patent Drafting
  • Patent Oppositions
  • Local and Foreign Patent Prosecution
  • Patentability advice
  • Inventorship analysis

Primary patent practice areas by technology:

  • Antibodies
  • Molecular and Cellular Biology
  • Immunology
  • Protein Biology
  • Gene Therapy including AAVs
  • CRISPR, siRNA and miRNA
  • Plant Biology and Agriculture
  • Diagnostics
  • Methods of Medical Treatment

Scientific/research background:

PhD research:

  • Characterised cellular pathways leading to renal interstitial fibrosis
  • Examined the role of epithelial-mesenchymal transition (EMT) in the pathogenesis of fibrosis

Postdoctoral research:

  • Examined the role of TGF-beta and Wnt signaling in the development of colorectal cancer
  • Examined the roles of key genes in skeletal muscle disease, cardiovascular disease and diabetes using an adeno-associated viral (AAV) gene therapy platform
  • Preclinical testing of AAVs and generation and testing of various AAV serotypes
  • Characterised the role of miRNA and siRNA in skeletal muscle disease and pathological cardiac hypertrophy
  • Characterised the role of miRNA in regulating the chromatin state of histone deacetylases via methylation and acetylation

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